Higly Cited Papers

2514 documents identified in the Top 1% most cited in the world.
Only 50 are listed. Click here to see the full list (it may take a while).

 
     

Document Citations 
1. 

Science. 2001; 291(5507):1304-+;  The sequence of the human genome .

Venter, JC; Adams, MD; Myers, EW; Li, PW; Mural, RJ; Sutton, GG; Smith, HO; Yandell, M; Evans, CA; Holt, RA; et. al.  +

5.882  at 31-12-2012  
(7.195 at 10-10-2014)  

Outstanding  
2. 

N Engl J Med. 2001; 344(11):783-792;  Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. .

Slamon, DJ; Leyland-Jones, B; Shak, S; Fuchs, H; Paton, V; Bajamonde, A; Fleming, T; Eiermann, W; Wolter, J; Pegram, M; et. al.  +

3.923  at 31-12-2012  
(4.781 at 17-06-2014)  

Outstanding  
3. 

N Engl J Med. 2002; 347(13):975-982;  Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection. .

Fried, Michael W; Shiffman, Mitchell L; Reddy, K Rajender; Smith, Coleman; Marinos, George; Gonçales, Fernando L; Häussinger, Dieter; Diago, Moises; Carosi, Giampiero; Dhumeaux, Daniel; et. al.  +

3.398  at 31-12-2012  
(4.043 at 17-06-2014)  

Outstanding  
4. 

Bioinformatics. 2003; 19(18):2496-2497;  DnaSP, DNA polymorphism analyses by the coalescent and other methods .

Rozas, Julio; Sánchez-DelBarrio, Juan C; Messeguer, Xavier; Rozas, Ricardo  +

3.369  at 31-12-2012  
(4.057 at 17-06-2014)  

Outstanding  
5. 

Science. 2000; 287(5461):2185-2195;  The genome sequence of Drosophila melanogaster .

Adams, MD; Celniker, SE; Holt, RA; Evans, CA; Gocayne, JD; Amanatides, PG; Scherer, SE; Li, PW; Hoskins, RA; Galle, RF; et. al.  +

3.181  at 31-12-2012  
(6.112 at 17-06-2014)  

Outstanding  
6. 

Nature. 2002; 420(6915):520-562;  Initial sequencing and comparative analysis of the mouse genome .

Waterston, RH; Lindblad-Toh, K; Birney, E; Rogers, J; Abril, JF; Agarwal, P; Agarwala, R; Ainscough, R; Alexandersson, M; An, P; et. al.  +

3.067  at 31-12-2012  
(3.663 at 10-10-2014)  

Outstanding  
7. 

N Engl J Med. 2001; 344(10):699-709;  Efficacy and safety of recombinant human activated protein C for severe sepsis. .

Bernard, GR; Vincent, JL; Laterre, PF; LaRosa, SP; Dhainaut, JF; Lopez-Rodriguez, A; Steingrub, JS; Garber, GE; Helterbrand, JD; Ely, EW; et. al.  +

3.020  at 31-12-2012  
(3.450 at 17-06-2014)  

Outstanding  
8. 

J Pathol. 1999; 189(1):12-19;  Human papillomavirus is a necessary cause of invasive cervical cancer worldwide .

Walboomers, JM; Jacobs, MV; Manos, MM; Bosch, FX; Kummer, JA; Shah, KV; Snijders, PJ; Peto, J; Meijer, CJ; Muñoz, N  +

2.965  at 31-12-2012  
(3.774 at 10-10-2014)  

Outstanding  
9. 

Nature. 2001; 411(6837):599-603;  Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease .

Hugot, JP; Chamaillard, M; Zouali, H; Lesage, S; Cézard, JP; Belaiche, J; Almer, S; Tysk, C; O'Morain, CA; Gassull, M; et. al.  +

2.546  at 31-12-2012  
(2.978 at 17-06-2014)  

Outstanding  
10. 

Science. 1997; 275(5297):218-220;  Cancer chemopreventive activity of resveratrol, a natural product derived from grapes .

Jang, M; Cai, EN; Udeani, GO; Slowing, KV; Thomas, CF; Beecher, CW; Fong, HH; Farnsworth, NR; Kinghorn, AD; Mehta, RG; et. al.  +

2.350  at 31-12-2012  
(2.931 at 17-06-2014)  

11. 

Nature. 1997; 390(6657):249-256;  The complete genome sequence of the Gram-positive bacterium Bacillus subtilis .

Kunst, F; Ogasawara, N; Moszer, I; Albertini, AM; Alloni, G; Azevedo, V; Bertero, MG; Bessières, P; Bolotin, A; Borchert, S; et. al.  +

2.284  at 31-12-2012  
(6.385 at 17-06-2014)  

Outstanding  
12. 

J Hypertens. 2003; 21(6):1011-1053;  2003 European society of hypertension - European Society of Cardiology guidelines for the management of arterial hypertension .

Mancia, G; Rosei, EA; Cifkova, R; DeBacker, G; Erdine, S; Fagard, R; Farsang, C; Heagerty, AM; Kawecka-Jaszcs, K; Kiowski, W; et. al.  +

2.180  at 31-12-2012  
(2.326 at 17-06-2014)  

Outstanding  
13. 

N Engl J Med. 2003; 348(6):518-527;  Epidemiologic classification of human papillomavirus types associated with cervical cancer .

Muñoz, Nubia; Bosch, F Xavier; de Sanjosé, Silvia; Herrero, Rolando; Castellsagué, Xavier; Shah, Keerti V; Snijders, Peter J F; Meijer, Chris J L M; Int Agcy Res Canc Multicenter Cerv  +

2.163  at 31-12-2012  
(2.844 at 10-10-2014)  

Outstanding  
14. 

Mol Biol Evol. 2008; 25(7):1253-1256;  jModelTest: Phylogenetic model averaging .

Posada, David  +

1.893  at 31-12-2012  
(3.422 at 17-06-2014)  

Outstanding  
15. 

Science. 1999; 285(5429):901-906;  Functional characterization of the S-cerevisiae genome by gene deletion and parallel analysis .

Winzeler, EA; Shoemaker, DD; Astromoff, A; Liang, H; Anderson, K; Andre, B; Bangham, R; Benito, R; Boeke, JD; Bussey, H; et. al.  +

1.870  at 31-12-2012  
(2.164 at 17-06-2014)  

Outstanding  
16. 

Cell. 1999; 97(6):703-716;  Subventricular zone astrocytes are neural stem cells in the adult mammalian brain .

Doetsch, F; Caillé, I; Lim, DA; García-Verdugo, JM; Alvarez-Buylla, A  +

1.822  at 31-12-2012  
(2.153 at 17-06-2014)  

Outstanding  
17. 

Methods Enzymol. 1999; 299:152-178;  Analysis of total phenols and other oxidation substrates and antioxidants by means of Folin-Ciocalteu reagent .

Singleton, VL; Orthofer, R; Lamuela-Raventos, RM  +

1.780  at 31-12-2012  
(2.591 at 17-06-2014)  

Outstanding  
18. 

Hepatology. 2005; 42(5):1208-1236;  Management of hepatoceullular carcinoma .

Bruix, J; Sherman, M  +

1.773  at 31-12-2012  
(2.505 at 17-06-2014)  

Outstanding  
19. 

J Hepatol. 2001; 35(3):421-430;  Clinical management of hepatocellular carcinoma. Conclusions of the Barcelona-2000 EASL Conference .

Bruix, J; Sherman, M; Llovet, JM; Beaugrand, M; Lencioni, R; Burroughs, AK; Christensen, E; Pagliaro, L; Colombo, M; Rodes, J; et. al.  +

1.754  at 31-12-2012  
(2.227 at 17-06-2014)  

Outstanding  
20. 

J Clin Oncol. 2000; 18(16):2938-2947;  Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer .

de Gramont, A; Figer, A; Seymour, M; Homerin, M; Hmissi, A; Cassidy, J; Boni, C; Cortes-Funes, H; Cervantes, A; Freyer, G; et. al.  +

1.751  at 31-12-2012  
(1.986 at 17-06-2014)  

Outstanding  
21. 

Blood. 1997; 89(6):2079-2088;  International scoring system for evaluating prognosis in myelodysplastic syndromes .

Greenberg, P; Cox, C; LeBeau, MM; Fenaux, P; Morel, P; Sanz, G; Sanz, M; Vallespi, T; Hamblin, T; Oscier, D; et. al.  +

1.727  at 31-12-2012  
(2.152 at 17-06-2014)  

Outstanding  
22. 

Lancet. 2000; 355(9209):1041-1047;  Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial .

Douillard, JY; Cunningham, D; Roth, AD; Navarro, M; James, RD; Karasek, P; Jandik, P; Iveson, T; Carmichael, J; Alakl, M; et. al.  +

1.694  at 31-12-2012  
(1.919 at 17-06-2014)  

Outstanding  
23. 

Nature. 2006; 444(7118):444-454;  Global variation in copy number in the human genome .

Redon, Richard; Ishikawa, Shumpei; Fitch, Karen R; Feuk, Lars; Perry, George H; Andrews, T Daniel; Fiegler, Heike; Shapero, Michael H; Carson, Andrew R; Chen, Wenwei; et. al.  +

1.678  at 31-12-2012  
(2.117 at 17-06-2014)  

Outstanding  
24. 

N Engl J Med. 2008; 359(4):378-390;  Sorafenib in advanced hepatocellular carcinoma .

Llovet, Josep M; Ricci, Sergio; Mazzaferro, Vincenzo; Hilgard, Philip; Gane, Edward; Blanc, Jean-Frédéric; de Oliveira, Andre Cosme; Santoro, Armando; Raoul, Jean-Luc; Forner, Alejandro; et. al.  +

1.668  at 31-12-2012  
(2.637 at 17-06-2014)  

Outstanding  
25. 

J Clin Oncol. 2003; 21(12):2237-2246;  Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer .

Fukuoka, Masahiro; Yano, Seiji; Giaccone, Giuseppe; Tamura, Tomohide; Nakagawa, Kazuhiko; Douillard, Jean-Yves; Nishiwaki, Yutaka; Vansteenkiste, Johan; Kudoh, Shinzoh; Rischin, Danny; et. al.  +

1.658  at 31-12-2012  
(1.993 at 17-06-2014)  

Outstanding  
26. 

N Engl J Med. 2005; 353(16):1659-1672;  Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer .

Piccart-Gebhart, Martine J; Procter, Marion; Leyland-Jones, Brian; Goldhirsch, Aron; Untch, Michael; Smith, Ian; Gianni, Luca; Baselga, Jose; Bell, Richard; Jackisch, Christian; et. al.  +

1.657  at 31-12-2012  
(2.113 at 17-06-2014)  

Outstanding  
27. 

Nature. 2007; 447(7146):799-816;  Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project .

Birney, Ewan; Stamatoyannopoulos, John A.; Dutta, Anindya; Guigo, Roderic; Gingeras, Thomas R.; Margulies, Elliott H.; Weng, Zhiping; Snyder, Michael; Dermitzakis, Emmanouil T.; et. al.  +

1.650  at 31-12-2012  
(2.243 at 10-10-2014)  

Outstanding  
28. 

Am J Respir Crit Care Med. 2007; 176(6):532-555;  Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease - GOLD executive summary .

Rabe, Klaus F.; Hurd, Suzanne; Anzueto, Antonio; Barnes, Peter J.; Buist, Sonia A.; Calverley, Peter; Fukuchi, Yoshinosuke; Jenkins, Christine; Rodriguez-Roisin, Roberto; van Weel, Chris; et. al.  +

1.646  at 31-12-2012  
(2.349 at 17-06-2014)  

Outstanding  
29. 

Lancet. 1997; 350(9080):757-764;  Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension .

Staessen, JA; Fagard, R; Thijs, L; Celis, H; Arabidze, GG; Birkenhager, WH; Bulpitt, CJ; deLeeuw, PW; Dollery, CT; Fletcher, AE; et. al.  +

1.608  at 31-12-2012  
(1.758 at 17-06-2014)  

Outstanding  
30. 

N Engl J Med. 2001; 345(12):870-878;  The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes .

Parving, HH; Lehnert, H; Bröchner-Mortensen, J; Gomis, R; Andersen, S; Arner, P; Irbesartan Patients Type 2 Diabete  +

1.578  at 31-12-2012  
(1.782 at 17-06-2014)  

31. 

Nature. 2002; 418(6896):387-391;  Functional profiling of the Saccharomyces cerevisiae genome .

Giaever, Guri; Chu, Angela M; Ni, Li; Connelly, Carla; Riles, Linda; Véronneau, Steeve; Dow, Sally; Lucau-Danila, Ankuta; Anderson, Keith; André, Bruno; et. al.  +

1.569  at 31-12-2012  
(3.008 at 17-06-2014)  

32. 

Lancet. 2003; 362(9399):1907-1917;  Hepatocellular carcinoma .

Llovet, JM; Burroughs, A; Bruix, J  +

1.549  at 31-12-2012  
(2.098 at 17-06-2014)  

Outstanding  
33. 

Bioinformatics. 2009; 25(11):1451-1452;  DnaSP v5: a software for comprehensive analysis of DNA polymorphism data .

Librado, P.; Rozas, J.  +

1.534  at 31-12-2012  
(2.905 at 17-06-2014)  

Outstanding  
34. 

N Engl J Med. 2006; 354(6):567-578;  Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck .

Bonner, James A; Harari, Paul M; Giralt, Jordi; Azarnia, Nozar; Shin, Dong M; Cohen, Roger B; Jones, Christopher U; Sur, Ranjan; Raben, David; Jassem, Jacek; et. al.  +

1.494  at 31-12-2012  
(1.981 at 17-06-2014)  

Outstanding  
35. 

N Engl J Med. 2002; 346(25):1937-1947;  The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma .

Rosenwald, A; Wright, G; Chan, WC; Connors, JM; Campo, E; Fisher, RI; Gascoyne, RD; Muller-Hermelink, HK; Smeland, EB; Staudt, LM; et. al.  +

1.438  at 31-12-2012  
(1.768 at 17-06-2014)  

Outstanding  
36. 

N Engl J Med. 2003; 348(11):994-1004;  Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia .

O'Brien, Stephen G; Guilhot, François; Larson, Richard A; Gathmann, Insa; Baccarani, Michele; Cervantes, Francisco; Cornelissen, Jan J; Fischer, Thomas; Hochhaus, Andreas; Hughes, Timothy; et. al.  +

1.424  at 31-12-2012  
(1.688 at 17-06-2014)  

37. 

Nature. 2003; 421(6920):231-237;  Systematic functional analysis of the Caenorhabditis elegans genome using RNAi .

Kamath, Ravi S; Fraser, Andrew G; Dong, Yan; Poulin, Gino; Durbin, Richard; Gotta, Monica; Kanapin, Alexander; Le Bot, Nathalie; Moreno, Sergio; Sohrmann, Marc; et. al.  +

1.404  at 31-12-2012  
(2.023 at 17-06-2014)  

38. 

Nature. 2006; 444(7117):337-342;  Resveratrol improves health and survival of mice on a high-calorie diet .

Baur, Joseph A; Pearson, Kevin J; Price, Nathan L; Jamieson, Hamish A; Lerin, Carles; Kalra, Avash; Prabhu, Vinayakumar V; Allard, Joanne S; Lopez-Lluch, Guillermo; Lewis, Kaitlyn; et. al.  +

1.273  at 31-12-2012  
(1.743 at 17-06-2014)  

Outstanding  
39.  1.269  at 31-12-2012  
(1.591 at 17-06-2014)  

Outstanding  
40. 

Nat Cell Biol. 2000; 2(2):76-83;  The transcription factor Snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression .

Cano, A; Pérez-Moreno, MA; Rodrigo, I; Locascio, A; Blanco, MJ; del Barrio, MG; Portillo, F; Nieto, MA  +

1.262  at 31-12-2012  
(1.556 at 17-06-2014)  

41. 

J Thromb Haemost. 2006; 4(2):295-306;  International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS) .

Miyakis, S; Lockshin, MD; Atsumi, T; Branch, DW; Brey, RL; Cervera, R; Derksen, RHWM; De Groot, PG; Koike, T; Meroni, PL; et. al.  +

1.218  at 31-12-2012  
(1.677 at 17-06-2014)  

Outstanding  
42. 

Jama-J Am Med Assoc. 1997; 277(22):1775-1781;  Plasma homocysteine as a risk factor for vascular disease - The European concerted action project .

Graham, IM; Daly, LE; Refsum, HM; Robinson, K; Brattström, LE; Ueland, PM; Palma-Reis, RJ; Boers, GH; Sheahan, RG; Israelsson, B; et. al.  +

1.212  at 31-12-2012  
(1.338 at 17-06-2014)  

43. 

Cell. 1997; 91(1):25-34;  Telomere shortening and tumor formation by mouse cells lacking telomerase RNA .

Blasco, MA; Lee, HW; Hande, MP; Samper, E; Lansdorp, PM; DePinho, RA; Greider, CW  +

1.203  at 31-12-2012  
(1.362 at 17-06-2014)  

44.  1.197  at 31-12-2012  
(1.346 at 17-06-2014)  

Outstanding  
45. 

N Engl J Med. 2005; 352(11):1092-1102;  Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial .

Bresalier, Robert S; Sandler, Robert S; Quan, Hui; Bolognese, James A; Oxenius, Bettina; Horgan, Kevin; Lines, Christopher; Riddell, Robert; Morton, Dion; Lanas, Angel; et. al.  +

1.191  at 31-12-2012  
(1.406 at 17-06-2014)  

46. 

Eur Heart J. 2003; 24(11):987-1003;  Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project .

Conroy, RM; Pyörälä, K; Fitzgerald, AP; Sans, S; Menotti, A; De Backer, G; De Bacquer, D; Ducimetière, P; Jousilahti, P; Keil, U; et. al.  +

1.167  at 31-12-2012  
(1.499 at 17-06-2014)  

Outstanding  
47. 

N Engl J Med. 2009; 360(13):1320-1328;  Screening and Prostate-Cancer Mortality in a Randomized European Study .

Schröder, Fritz H; Hugosson, Jonas; Roobol, Monique J; Tammela, Teuvo L J; Ciatto, Stefano; Nelen, Vera; Kwiatkowski, Maciej; Lujan, Marcos; Lilja, Hans; Zappa, Marco; et. al.  +

1.159  at 31-12-2012  
(1.555 at 17-06-2014)  

Outstanding  
48. 

Lancet. 1998; 352(9136):1245-1251;  Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II) .

Hacke, W; Kaste, M; Fieschi, C; von Kummer, R; Davalos, A; Meier, D; Larrue, V; Bluhmki, E; Davis, S; Donnan, G; et. al.  +

1.151  at 31-12-2012  
(1.357 at 17-06-2014)  

Outstanding  
49. 

N Engl J Med. 2006; 355(23):2408-2417;  Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia .

Druker, Brian J; Guilhot, François; O'Brien, Stephen G; Gathmann, Insa; Kantarjian, Hagop; Gattermann, Norbert; Deininger, Michael W N; Silver, Richard T; Goldman, John M; Stone, Richard M; et. al.  +

1.149  at 31-12-2012  
(1.498 at 17-06-2014)  

Outstanding  
50. 

J Clin Pathol. 2002; 55(4):244-265;  The causal relation between human papillomavirus and cervical cancer .

Bosch, FX; Lorincz, A; Munoz, N; Meijer, CJLM; Shah, KV  +

1.145  at 31-12-2012  
(1.525 at 10-10-2014)  

Outstanding